Meningitis in Typhoid Fever

Management of Typhoid Fever and Bacterial Meningitis by Chloramphenicol in Infants and Children

Chloramphenicol inhibits protein synthesis in bacteria and is usually bacteriostatic but is bactericidal against Haemophilus influenzae, Streptococcus pneumoniae, and Neisseria meningitis. Chloramphenicol penetrates all body tissues well. The cerebrospinal fluid concentration averages 60% of the serum level, while brain levels are 9 times higher because of high lipid solubility of this drug. Ch...

HEMOPHAGOCYTIC SYNDROME IN TYPHOID FEVER AND BRUCELLOSIS

Hemophagocytic syndrome is a non-malignant process that is characterized clinically by fever, hepatomegaly, splenomegaly, pancytopenia in peripheral blood, and reactive histiocytes in the bone marrow. Bacterial infectious diseases like typhoid fever and brucellosis and viral infections including CMV, herpes viruses, and Epstein-Barr virus are diagnosed as the cause of this syndrome. In thi...

Typhoid Fever and Typhoid Carriers

Typhoid Fever

Between one and five percent of travelers from industrialized countries to the developing world seek medical attention during or immediately after their travel.1 International travelers who present to the emergency department (ED) with fever pose a unique challenge to the emergency physician (EP). In addition to the usual causes of fever, the EP must consider less common diseases in the differe...

Typhoid Fever

Introduction Typhoid or enteric fever is an ancient disease, which has afflicted mankind since human populations grew large enough to contaminate their water and food supplies. It is caused by Salmonella enterica serovar typhi (previously known as salmonella typhi), a pathogen specific only to humans, as well as by certain non-typhoid salmonella (NTS), particularly Paratyphoid strains A, B, C. ...